KIF7 antibody

Catalog No. ABIN6288850

Product Details anti-KIF7 Antibody

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This KIF7 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purpose: Kif 7 is a protein encoded by the KIF7 gene which is approximately 150,5 kDa. Kif 7 is localised to the cilium tip. It is involved in signalling by hedgehog and GPCR. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of a ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Kif 7 is expressed in embryonic stem cells and Jurkat T-cells. Mutations in the KIF7 gene may result in Bardet-Biedl syndrome. STJ96965 was developed from clone 3F8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous Kif 7 proteins.

Specificity: The antibody detects endogenous Kif 7 proteins.

Characteristics: Mouse monoclonal to Kif 7.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide

Clone: 3F8

Isotype: IgG1

Application Details

Application Notes: IHC 1:200

Comment:

Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for KIF7

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Alternative Name: Kif 7 (KIF7 Products)

Synonyms: KIF7 antibody, DDBDRAFT_0204609 antibody, DDBDRAFT_0206583 antibody, DDB_0204609 antibody, DDB_0206583 antibody, ACLS antibody, HLS2 antibody, JBTS12 antibody, UNQ340 antibody, cos2 antibody, costal2 antibody, kinesin family member 7 antibody, KIF7 antibody, kif7 antibody, Kif7 antibody

Gene ID: 374654

UniProt: Q2M1P5

Pathways: Hedgehog Signaling