KIF7 antibody (AA 1044-1343)

Catalog No. ABIN7268137

This Rabbit Polyclonal antibody specifically detects KIF7 in WB. It exhibits reactivity toward Human.

Quick Overview for KIF7 antibody (AA 1044-1343) (ABIN7268137)

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KIF7 Antibody

Binding Specificity: AA 1044-1343

Purpose: KIF7 Rabbit pAb

Sequence: QLDEAIEALD AAIEYKNEAI TCRQRVLRAS ASLLSQCEMN LMAKLSYLSS SETRALLCKY FDKVVTLREE QHQQQIAFSE LEMQLEEQQR LVYWLEVALE RQRLEMDRQL TLQQKEHEQN MQLLLQQSRD HLGEGLADSR RQYEARIQAL EKELGRYMWI NQELKQKLGG VNAVGHSRGG EKRSLCSEGR QAPGNEDELH LAPELLWLSP LTEGAPRTRE ETRDLVHAPL PLTWKRSSLC GEEQGSPEEL RQREAAEPLV GRVLPVGEAG LPWNFGPLSK PRRELRRASP GMIDVRKNPL

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1044-1343 of human KIF7 (NP_940927.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KIF7

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Alternative Name: KIF7

Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.,KIF7,ACLS,AGBK,HLS2,JBTS12,UNQ340,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Hedgehog Signaling Pathway,Stem Cells,KIF7

Molecular Weight: 150kDa

Gene ID: 374654

UniProt: Q2M1P5

Pathways: Hedgehog Signaling