EGF antibody (AA 1048-1077)
Quick Overview for EGF antibody (AA 1048-1077) (ABIN6294272)
Target
See all EGF AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 1048-1077
-
Purpose
- Rabbit Anti-EGFR (S1070) Antibody
-
Immunogen
- This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1048-1077 amino acids from human EGFR.
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- 2-8°C (short-term), -20°C (long-term)
-
-
- EGF (Epidermal Growth Factor (EGF))
-
Alternative Name
- EGF
-
Background
-
Target Description: The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
Gene Symbol: EGFR
-
Gene ID
- 1956
-
UniProt
- P00533
-
Pathways
- NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
Target
-