Transforming Protein Myb (AA 119-135) antibody

Catalog No. ABIN6294290

The Mouse Monoclonal anti-Transforming Protein Myb antibody is suitable to detect Transforming Protein Myb in samples from Human. It has been validated for FACS and IF.

Quick Overview for Transforming Protein Myb (AA 119-135) antibody (ABIN6294290)

Target: Transforming Protein Myb

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 119-135

Purpose: Mouse anti-Human c-Myb Antibody [Sodium Azide Free]

Specificity: Nuclear

Purification: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.

Immunogen: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details

Target: Transforming Protein Myb

Background:

Target Description: The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

Gene Symbol: V-MYB

UniProt: P01104