LGALS1/Galectin 1 antibody (AA 12-108)

Catalog No. ABIN6294291

This anti-LGALS1/Galectin 1 antibody is a Mouse Monoclonal antibody detecting LGALS1/Galectin 1 in WB, IHC, ELISA, FACS, IF and Coat. Suitable for Human.

Quick Overview for LGALS1/Galectin 1 antibody (AA 12-108) (ABIN6294291)

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LGALS1/Galectin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)

Product Details anti-LGALS1/Galectin 1 Antibody

Binding Specificity: AA 12-108

Purpose: Mouse anti-Human Galectin 1 Antibody [Sodium Azide Free]

Specificity: Cytoplasmic, secreted

Purification: A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.

Immunogen: A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.

Application Details

Application Notes: ELISA: 2-4 μg/mL, order the BSA-free formulation for coating
IF: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Alternative Name: Galectin-1

Background:

Target Description: Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

Gene Symbol: LGALS1

Gene ID: 3956

UniProt: P09382

Pathways: Carbohydrate Homeostasis