MMP2 antibody (AA 195-319)

Catalog No. ABIN6294360

This anti-MMP2 antibody is a Mouse Monoclonal antibody detecting MMP2 in WB. Suitable for Human.

Quick Overview for MMP2 antibody (AA 195-319) (ABIN6294360)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP2 Antibody

Binding Specificity: AA 195-319

Purpose: Mouse anti-Human MMP2 Antibody [Sodium Azide Free]

Specificity: Cytoplasmic, cell surface

Purification: Amino acids 195-319 were used as the immunogen for the MMP2 antibody.

Immunogen: Amino acids 195-319 were used as the immunogen for the MMP2 antibody.

Application Details

Application Notes: WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Alternative Name: 72 kDa type IV collagenase

Background:

Target Description: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP2 secretion requires the Ras signaling pathway.

Gene Symbol: MMP2///CLG4A

Gene ID: 4313

UniProt: P08253

Pathways: Activation of Innate immune Response