MMP2 antibody (Matrix Metalloproteinase 2) (AA 242-396)

Details for Product anti-MMP2 Antibody No. ABIN1098146, Supplier: Log in to see
Antigen
  • 2-MMP
  • CG1794
  • DM2-MMP
  • Dm2-MMP
  • Dmel\\CG1794
  • MMP2
  • anon-WO0118547.84
  • dm-2MMP
  • dmmp2
  • l(2)02353
  • mmp2
  • wu:fa99h12
  • wu:fk89d01
  • fgmmp-2
  • Mmp-2
  • LOC100135793
  • Clg4a
  • GelA
  • MMP-2
  • CLG4
  • CLG4A
  • MMP-II
  • MONA
  • TBE-1
  • matrix metallopeptidase 2
  • Matrix metalloproteinase 2
  • matrix metalloproteinase 2
  • matrix metalloproteinase-2
  • MMP2
  • Mmp2
  • mmp2
  • LOC657982
  • LOC100135793
Alternatives
anti-Rat (Rattus) MMP2 antibody for Immunoprecipitation
Epitope
AA 242-396
21
20
18
16
15
15
12
10
10
10
8
8
7
6
6
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
395
183
172
29
16
15
13
11
7
6
6
5
4
2
2
2
2
2
1
1
1
Host
Mouse
248
176
2
2
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This MMP2 antibody is un-conjugated
20
17
15
8
8
6
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
325
148
113
108
89
72
63
60
54
39
19
6
5
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of human MMP2 (AA 242-396) expressed in E. Coli.
Clone 4D1E2
Isotype IgG1
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others MMP2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name MMP2 (MMP2 Antibody Abstract)
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. , ,
Molecular Weight 73.8 kDa
Gene ID 4313
HGNC 4313
Pathways Activation of Innate immune Response
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
ELISA image for anti-Matrix Metalloproteinase 2 (MMP2) (AA 242-396) antibody (ABIN1098146) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Western Blotting (WB) image for anti-Matrix Metalloproteinase 2 (MMP2) (AA 242-396) antibody (ABIN1098146) Figure 2: Western blot analysis using MMP2 mouse mAb against A431 (1) cell lysate.
Western Blotting (WB) image for anti-Matrix Metalloproteinase 2 (MMP2) (AA 242-396) antibody (ABIN1098146) Figure 3: Western blot analysis using MMP2 mAb against human MMP2 recombinant protein...
Product cited in: Langers, Verspaget, Hawinkels, Kubben, van Duijn, van der Reijden, Hardwick, Hommes, Sier: "MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients." in: British journal of cancer, Vol. 106, Issue 9, pp. 1495-8, 2012 (PubMed).

Hajighasemi: "Profiles of MMP-2 expression in Jurkat, Molt-4 and U937 cells." in: Iranian journal of immunology : IJI, Vol. 8, Issue 2, pp. 120-6, 2011 (PubMed).

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