BCL2L1 antibody (AA 3-14)

Catalog No. ABIN6294448

This Mouse Monoclonal antibody specifically detects BCL2L1 in WB, IHC, IF and FACS. It exhibits reactivity toward Human, Mouse, Rat and Pig.

Quick Overview for BCL2L1 antibody (AA 3-14) (ABIN6294448)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivity: Human, Mouse, Rat, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL2L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-BCL2L1 Antibody

Binding Specificity: AA 3-14

Purpose: Mouse anti-Human/Mouse/Rat/Pig Bcl-X Antibody [Sodium Azide Free]

Specificity: Cytoplasmic, cell and nuclear membrane

Purification: A synthetic peptide, aa 3-14 (c-QSNRELVVDFLS) from the human protein was used as the immunogen for the Bcl-X antibody.

Immunogen: A synthetic peptide, aa 3-14 (c-QSNRELVVDFLS) from the human protein was used as the immunogen for the Bcl-X antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Alternative Name: Bcl-2-like protein 1

Background:

Target Description: Recognizes a protein of 27 kDa, identified as the Bcl-X protein. This mAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This mAb reacts with both Bcl-XS and Bcl-XL proteins.

Gene Symbol: BCL2L1///BCL2L///BCLX

Gene ID: 598

UniProt: Q07817

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling