TGFA antibody (C-Term)

Catalog No. ABIN6294628

This Mouse Monoclonal antibody specifically detects TGFA in IF and FACS. It exhibits reactivity toward Human, Rat, Mouse and Cow.

Quick Overview for TGFA antibody (C-Term) (ABIN6294628)

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Reactivity: Human, Rat, Mouse, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGFA antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-TGFA Antibody

Binding Specificity: C-Term

Purpose: Mouse anti-Human/Cow/Rat/Mouse TGF-a Antibody [Sodium Azide Free]

Specificity: Cytoplasmic and Extracellular (secreted)

Purification: A 17-amino acid peptide from the C-terminus of the rat protein was used as the immunogen for this TGF a antibody.

Immunogen: A 17-amino acid peptide from the C-terminus of the rat protein was used as the immunogen for this TGF a antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for TGFA

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Alternative Name: Protransforming growth factor alpha

Background:

Target Description: This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF-a is a growth factor with 33 % homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Gene Symbol: TGFA

Gene ID: 7039

UniProt: P01135

Pathways: NF-kappaB Signaling, RTK Signaling, EGFR Signaling Pathway