CSE1L antibody (C-Term)

Catalog No. ABIN6295024

This Rabbit Polyclonal antibody specifically detects CSE1L in . It exhibits reactivity toward Human and Mouse.

Quick Overview for CSE1L antibody (C-Term) (ABIN6295024)

Target: CSE1L (Chromosome Segregation 1-Like (CSE1L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSE1L antibody is un-conjugated

Application: Please inquire

Product Details anti-CSE1L Antibody

Binding Specificity: AA 55-84, C-Term

Purpose: Rabbit Anti-Cellular Apoptosis Susceptibility (C-term) Antibody

Immunogen: This Cellular Apoptosis Susceptibility antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the C-terminal region of human Cellular Apoptosis Susceptibility.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CSE1L

Target: CSE1L (Chromosome Segregation 1-Like (CSE1L))

Alternative Name: Cellular Apoptosis Susceptibility

Background:

Target Description: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.

Gene Symbol: CSE1L

Gene ID: 1434

UniProt: P55060