VRK1 antibody (Center)

Catalog No. ABIN6295345

This Rabbit Polyclonal antibody specifically detects VRK1 in . It exhibits reactivity toward Human and Mouse.

Quick Overview for VRK1 antibody (Center) (ABIN6295345)

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VRK1 antibody is un-conjugated

Application: Please inquire

Product Details anti-VRK1 Antibody

Binding Specificity: AA 366-396, Center

Purpose: Rabbit Anti-VRK1 (Center) Antibody

Immunogen: This VRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-396 amino acids from the Central region of human VRK1.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for VRK1

Target: VRK1 (Vaccinia Related Kinase 1 (VRK1))

Alternative Name: VRK1

Background:

Target Description: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Gene Symbol: VRK1

Gene ID: 7443

UniProt: Q99986