Plakophilin 1 antibody (N-Term)

Catalog No. ABIN6295517

The Mouse Monoclonal anti-Plakophilin 1 antibody has been validated for WB and IF. It is suitable to detect Plakophilin 1 in samples from Human and Mouse.

Quick Overview for Plakophilin 1 antibody (N-Term) (ABIN6295517)

Target: Plakophilin 1 (PKP1)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Plakophilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Plakophilin 1 Antibody

Binding Specificity: AA 1-27, N-Term

Purpose: Mouse anti-Human/Mouse Plakophilin 1 Antibody [Sodium Azide Free]

Specificity: Cell surface, nuclear

Purification: A N-terminal human recombinant protein fragment was used as the immunogen for the Plakophilin 1 antibody. Its epitope maps to between amino acids 1-27 of human PKP1.

Immunogen: A N-terminal human recombinant protein fragment was used as the immunogen for the Plakophilin 1 antibody. Its epitope maps to between amino acids 1-27 of human PKP1.

Application Details

Application Notes: WB: 0.5-1 μg/mL
IF: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Plakophilin 1

Target: Plakophilin 1 (PKP1)

Alternative Name: Plakophilin-1

Background:

Target Description: Recognizes a protein of 75 kDa, identified as Plakophilin 1 (PKP1). Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. PKP1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). PKP2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.

Gene Symbol: PKP1

Gene ID: 5317

UniProt: Q13835