Desmoglein 3 antibody

Catalog No. ABIN6296083

This Mouse Monoclonal antibody specifically detects Desmoglein 3 in WB, IF, FACS and IP. It exhibits reactivity toward Human.

Quick Overview for Desmoglein 3 antibody (ABIN6296083)

Target: Desmoglein 3 (DSG3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Desmoglein 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)

Product Details anti-Desmoglein 3 Antibody

Purpose: Mouse anti-Human Desmoglein 3 Antibody / DSG3 [Sodium Azide Free]

Specificity: Cell surface

Purification: A recombinant human protein corresponding to the extracellular portion of DSG3 was used as the immunogen for the Desmoglein 3 antibody.

Immunogen: A recombinant human protein corresponding to the extracellular portion of DSG3 was used as the immunogen for the Desmoglein 3 antibody.

Application Details

Application Notes: WB: 0.5-1 μg/mL
FACS: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunoprecipitation: suitable

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Desmoglein 3

Target: Desmoglein 3 (DSG3)

Alternative Name: Desmoglein-3

Background:

Target Description: Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.

Gene Symbol: DSG3///CDHF6

Gene ID: 1830

UniProt: P32926