alpha Fetoprotein antibody

Catalog No. ABIN6296146

This Mouse Monoclonal antibody specifically detects alpha Fetoprotein in IF, FACS and IHC (fp). It exhibits reactivity toward Human, Pig, Dog and Monkey.

Quick Overview for alpha Fetoprotein antibody (ABIN6296146)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivity: Human, Pig, Dog, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha Fetoprotein antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-alpha Fetoprotein Antibody

Purpose: Mouse anti-Human/Monkey/Dog/Pig AFP Antibody Alpha Fetoprotein [Sodium Azide Free]

Specificity: Cytoplasmic

Purification: Alpha fetoprotein purified from serum of a hepatoma patient was used as the immunogen for this AFP antibody.

Immunogen: Alpha fetoprotein purified from serum of a hepatoma patient was used as the immunogen for this AFP antibody.

Application Details

Application Notes: FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL,IHC(FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Alternative Name: Alpha-fetoprotein

Background:

Target Description: This antibody recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as Alpha fetoprotein (AFP). The AFP antibody is highly specific and shows no cross-reaction with other oncofetal antigens or serum albumin. Alpha fetoprotein is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. AFP antibody has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Gene Symbol: AFP///HPAFP

Gene ID: 174

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process