CD2 antibody

Catalog No. ABIN6296614

This Mouse Monoclonal antibody specifically detects CD2 in FACS, IF, WB and Func. It exhibits reactivity toward Human and Cat.

Quick Overview for CD2 antibody (ABIN6296614)

Target: CD2

Reactivity: Human, Cat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)

Product Details anti-CD2 Antibody

Purpose: Mouse anti-Human/Cat CD2 Antibody [Sodium Azide Free]

Specificity: Cell surface

Purification: Human thymocytes were used as the immunogen for the CD2 antibody.

Immunogen: Human thymocytes were used as the immunogen for the CD2 antibody.

Application Details

Application Notes: Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Western blot: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD2

Target: CD2

Alternative Name: T-cell surface antigen CD2

Background:

Target Description: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Gene Symbol: CD2///SRBC

Gene ID: 914

UniProt: P06729