MYH11 antibody

Catalog No. ABIN6296638

This Mouse Monoclonal antibody specifically detects MYH11 in IHC, IF and FACS. It exhibits reactivity toward Human, Rat, Cat, Chicken, Cow, Dog, Guinea Pig, Pig and Rabbit.

Quick Overview for MYH11 antibody (ABIN6296638)

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Reactivity: Human, Rat, Cat, Chicken, Cow, Dog, Guinea Pig, Pig, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This MYH11 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-MYH11 Antibody

Purpose: Mouse anti-Human/Cow/Pig/Dog/Cat/Rabbit/Rat/Guinea Pig/Chicken SM-MHC Antibody [Sodium Azide Free]

Specificity: Cytoplasmic

Purification: Human uterus extract was used as the immunogen for the SM-MHC antibody.

Immunogen: Human uterus extract was used as the immunogen for the SM-MHC antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for MYH11

Target: MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))

Alternative Name: Myosin-11

Background:

Target Description: Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Gene Symbol: MYH11///KIAA0866

Gene ID: 4629

UniProt: P35749