IGHG1 antibody

Catalog No. ABIN6296843

Product Details anti-IGHG1 Antibody

Target: IGHG1 (Immunoglobulin Heavy Constant gamma 1 (IGHG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGHG1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Mouse anti-Human IgG Antibody [IHC only]

Specificity: Cytoplasm, Cell Surface and Secreted

Purification: Purified human Ig Gamma Chain was used as the immunogen for this IgG antibody.

Immunogen: Purified human Ig Gamma Chain was used as the immunogen for this IgG antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for IGHG1

Target: IGHG1 (Immunoglobulin Heavy Constant gamma 1 (IGHG1))

Alternative Name: Immunoglobulin heavy constant gamma 1 (IGHG1 Products)

Background:

Target Description: Recognizes a protein of 75 kDa, identified as gamma heavy chain of human immunoglobulins. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Gene Symbol: IGHG1///IGHG2///IGHG3///IGHG4

Gene ID: 3500

UniProt: P01857, P01859, P01860, P01861