CDK1 antibody

Catalog No. ABIN6296888

The Mouse Monoclonal anti-CDK1 antibody is suitable to detect CDK1 in samples from Human, Monkey, Cow and Mink. It has been validated for IHC, IF and FACS.

Quick Overview for CDK1 antibody (ABIN6296888)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivity: Human, Monkey, Cow, Mink

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-CDK1 Antibody

Purpose: Mouse anti-Human/Monkey/Cow/Mink Cdk1 Antibody [Sodium Azide Free]

Specificity: Nuclear and cell surface

Purification: Purified recombinant human Cdk1 / p34cdc2 was used as the immunogen for this Cdk1 antibody.

Immunogen: Purified recombinant human Cdk1 / p34cdc2 was used as the immunogen for this Cdk1 antibody.

Application Details

Application Notes: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE) only: 1-2 μg/mL (1)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Alternative Name: Cyclin-dependent kinase 1

Background:

Target Description: This antibody recognizes a 34 kDa protein, which is identified as cyclin dependent kinase 1 (Cdk1) or p34cdc2 protein kinase. CDK1 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated CDK1 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.

Gene Symbol: CDK1///CDC2///CDC28A///CDKN1///P34CDC2

Gene ID: 983

UniProt: P06493

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA