OTC antibody (N-Term)

Catalog No. ABIN629690

The Rabbit Polyclonal anti-OTC antibody has been validated for WB and IHC. It is suitable to detect OTC in samples from Human, Mouse, Rat and Dog.

Quick Overview for OTC antibody (N-Term) (ABIN629690)

Target: OTC (Ornithine Carbamoyltransferase (OTC))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-OTC Antibody

Binding Specificity: N-Term

Specificity: OTC antibody was raised against the N terminal of OTC

Purification: Purified

Immunogen: OTC antibody was raised using the N terminal of OTC corresponding to a region with amino acids AFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTGEEIKYMLWLSAD

Application Details

Application Notes: WB: 2.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

OTC Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this OTC antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of OTC antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for OTC

Target: OTC (Ornithine Carbamoyltransferase (OTC))

Alternative Name: OTC

Background: OTC is a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

Molecular Weight: 39 kDa (MW of target protein)