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FECH antibody

This anti-FECH antibody is a Rabbit Polyclonal antibody detecting FECH in WB. Suitable for Human, Mouse, Rat and Dog.
Catalog No. ABIN629703

Quick Overview for FECH antibody (ABIN629703)

Target

See all FECH Antibodies
FECH (Ferrochelatase (FECH))

Reactivity

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Human, Mouse, Rat, Dog

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This FECH antibody is un-conjugated

Application

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Western Blotting (WB)
  • Purification

    Purified

    Immunogen

    FECH antibody was raised using a synthetic peptide corresponding to a region with amino acids LDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGM
  • Application Notes

    WB: 2.5 µg/mL
    Optimal conditions should be determined by the investigator.

    Comment

    FECH Blocking Peptide, (ABIN940246), is also available for use as a blocking control in assays to test for specificity of this FECH antibody

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FECH antibody in PBS

    Concentration

    Lot specific

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target

    FECH (Ferrochelatase (FECH))

    Alternative Name

    FECH

    Background

    Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria.Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight

    47 kDa (MW of target protein)

    Pathways

    Transition Metal Ion Homeostasis
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