alpha Actinin 4 antibody (N-Term)
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- Target See all alpha Actinin 4 (ACTN4) Antibodies
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This alpha Actinin 4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- Alpha Actinin 4 antibody was raised against the N terminal of ACTN4
- Purification
- Purified
- Immunogen
- alpha Actinin 4 antibody was raised using the N terminal of ACTN4 corresponding to a region with amino acids LIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDIVNTA
- Top Product
- Discover our top product ACTN4 Primary Antibody
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- Application Notes
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WB: 0.625 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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Alpha Actinin 4 Blocking Peptide, catalog no. 33R-5045, is also available for use as a blocking control in assays to test for specificity of this Alpha Actinin 4 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ACTN4 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- Alternative Name
- alpha Actinin 4 (ACTN4 Products)
- Synonyms
- fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody
- Background
- Alpha actinins belong to the spectrin superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Alpha actinin is an actin-binding protein with multiple roles in different cell types.
- Molecular Weight
- 100 kDa (MW of target protein)
- Pathways
- Proton Transport
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