Tyrosinase  (TYR) antibody

Details for Product No. ABIN6297625
Antigen
  • sandy
  • zgc:109705
  • TYR
  • TYRO
  • tyr
  • LOC100136546
  • CMM8
  • OCA1A
  • OCAIA
  • SHEP3
  • albino
  • c
  • skc35
  • C
  • tyrosinase
  • TYRosinase
  • tyrosinase S homeolog
  • tyr
  • tyr-5
  • tyr.S
  • TYR
  • Celal_3121
  • Halhy_4121
  • Mesop_2736
  • LOC100136546
  • Tyr
Reactivity
Human
256
45
39
10
7
6
6
5
2
2
2
2
2
1
1
1
1
Host
Mouse
139
133
2
Clonality
Monoclonal
Conjugate
Un-conjugated
10
6
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
125
124
98
81
81
63
57
23
20
15
13
12
11
10
3
1
Options
Purpose Mouse anti-Human Tyrosinase Antibody [Sodium Azide Free]
Immunogen Recombinant Tyrosinase protein was used as the immunogen for this antibody.
Specificity Cytoplasmic
Purification Recombinant Tyrosinase protein was used as the immunogen for this antibody.
Antigen
Alternative Name Tyrosinase (TYR Antibody Abstract)
Background

Target Description: Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.

Gene Symbol: TYR

Gene ID 7299
UniProt P14679
Application Notes Western blot: 2-5 μg/mL
FACS:0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS ( pH 7.4), BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Did you look for something else?