CD1b antibody

Catalog No. ABIN6297677

Product Details anti-CD1b Antibody

Target: CD1b (CD1B)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Purpose: Mouse anti-Human CD1b Antibody [Sodium Azide Free]

Specificity: Cell surface

Purification: Stimulated human leukocytes were used as the immunogen for the CD1b antibody.

Immunogen: Stimulated human leukocytes were used as the immunogen for the CD1b antibody.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Functional Activity (Order SAF formulation)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD1b

Target: CD1b (CD1B)

Alternative Name: T-cell surface glycoprotein CD1b (CD1B Products)

Synonyms: CD1 antibody, CD1A antibody, R1 antibody, CD1B3 antibody, CD1B antibody, CD1-b antibody, CD1b molecule antibody, T-cell surface glycoprotein CD1b-3 antibody, CD1b1 molecule antibody, T-cell surface glycoprotein CD1b1 antibody, CD1B antibody, LOC443423 antibody, CD1B1 antibody, LOC100720602 antibody

Background:

Target Description: The mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV, Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.

Gene Symbol: CD1B

Gene ID: 910

UniProt: P29016