CD68 antibody

Catalog No. ABIN6297781

This Mouse Monoclonal antibody specifically detects CD68 in IHC. It exhibits reactivity toward Human, Mouse, Monkey, Rat and Cat.

Quick Overview for CD68 antibody (ABIN6297781)

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Human, Mouse, Monkey, Rat, Cat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CD68 Antibody

Purpose: Mouse anti-Human/Monkey/Mouse/Rat/Cat CD68 Antibody [IHC only]

Specificity: Cytoplasmic, membrane

Purification: The subcellular fraction of human alveolar macrophages was used as the immunogen for this CD68 antibody.

Immunogen: The subcellular fraction of human alveolar macrophages was used as the immunogen for this CD68 antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: Macrosialin

Background:

Target Description: This antibody recognizes a glycoprotein of 110 kDa, which is identified as CD68. antibody to CD68 is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. CD68 antibody reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. CD68 shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

Gene Symbol: CD68

Gene ID: 968

UniProt: P34810