HSP70 1A antibody (Biotin)

Catalog No. ABIN6297835

This Rabbit Polyclonal antibody specifically detects HSP70 1A in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for HSP70 1A antibody (Biotin) (ABIN6297835)

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP70 1A antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Product Details anti-HSP70 1A Antibody (Biotin)

Purpose: Rabbit anti-Human HSPA1A Biotinylated Antibody

Immunogen: This antibody was produced from antiserum of rabbits immunized with a recombinant protein immunogen. The IgG fraction was purified by Protein G/A affinity chromatography.

Application Details

Application Notes: ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)

Restrictions: For Research Use only

Handling

Reconstitution: A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: -20°C

Target Details for HSP70 1A

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Alternative Name: HSPA1A

Background:

Target Description: Heat shock 70 kDa protein 1  is a  protein  that in humans is encoded by the  HSPA1A  gene. This  intronless  gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

UniProt: P08107

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process