MUSK antibody (Muscle, Skeletal, Receptor Tyrosine Kinase)

Details for Product anti-MUSK Antibody No. ABIN6297871
Antigen
  • unp
  • fj98e12
  • zgc:63467
  • wu:fj98e12
  • si:dz46m7.2
  • si:dz57f23.3
  • si:busm1-57f23.3
  • musk-A
  • MuSK
  • MUSK
  • Mdk4
  • Mlk
  • Nsk1
  • Nsk2
  • Nsk3
  • muscle
  • muscle associated receptor tyrosine kinase
  • muscle, skeletal, receptor tyrosine kinase
  • muscle associated receptor tyrosine kinase S homeolog
  • MUSK
  • musk
  • musk.S
  • Musk
Reactivity
Human, Mouse (Murine)
139
71
62
2
2
1
1
1
1
1
Host
Rabbit
119
27
3
Clonality
Polyclonal
Conjugate
This MUSK antibody is un-conjugated
7
5
5
4
4
4
3
3
3
3
3
3
1
1
1
1
1
Application
113
83
67
32
24
13
10
5
5
5
5
3
1
Options
Purpose Rabbit Anti-MUSK Antibody
Immunogen This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.
Plasmids, Primers & others Plasmids, Primers & others MUSK products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name MUSK (MUSK Antibody Abstract)
Background

Target Description: MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.

Gene Symbol: MUSK
Gene ID 4593
UniProt O15146
Pathways RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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