MUSK antibody
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- Target See all MUSK Antibodies
- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MUSK antibody is un-conjugated
- Application
- Please inquire
- Purpose
- Rabbit Anti-MUSK Antibody
- Immunogen
- This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.
- Top Product
- Discover our top product MUSK Primary Antibody
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- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
- Alternative Name
- MUSK (MUSK Products)
- Background
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Target Description: MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Gene Symbol: MUSK
- Gene ID
- 4593
- UniProt
- O15146
- Pathways
- RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
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