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MUSK antibody (AA 829-859)

MUSK Reactivity: Human FACS, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031878
$578.58
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  • Target See all MUSK Antibodies
    MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
    Binding Specificity
    • 15
    • 12
    • 9
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 829-859
    Reactivity
    • 82
    • 29
    • 25
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 73
    • 11
    • 2
    Rabbit
    Clonality
    • 78
    • 11
    Polyclonal
    Conjugate
    • 39
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MUSK antibody is un-conjugated
    Application
    • 57
    • 43
    • 38
    • 20
    • 17
    • 13
    • 12
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    Purified
    Immunogen
    A portion of amino acids 829-859 from the human protein was used as the immunogen for this MUSK antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the MUSK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the MUSK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
    Alternative Name
    MUSK (MUSK Products)
    Synonyms
    unp antibody, fj98e12 antibody, zgc:63467 antibody, wu:fj98e12 antibody, si:dz46m7.2 antibody, si:dz57f23.3 antibody, si:busm1-57f23.3 antibody, musk-A antibody, MuSK antibody, MUSK antibody, Mdk4 antibody, Mlk antibody, Nsk1 antibody, Nsk2 antibody, Nsk3 antibody, muscle antibody, muscle associated receptor tyrosine kinase antibody, muscle, skeletal, receptor tyrosine kinase antibody, muscle associated receptor tyrosine kinase S homeolog antibody, MUSK antibody, musk antibody, musk.S antibody, Musk antibody
    Background
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
    UniProt
    O15146
    Pathways
    RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
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