Calreticulin antibody
Quick Overview for Calreticulin antibody (ABIN6297924)
Target
See all Calreticulin (CALR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Rabbit Anti-CALR Antibody,
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Restrictions
- For Research Use only
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Calreticulin (CALR)
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Alternative Name
- CALR
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Background
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Target Description: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).
Gene Symbol: CALR
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Gene ID
- 811
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UniProt
- P27797
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Pathways
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
Target
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