Calreticulin antibody

Catalog No. ABIN6297924

The Rabbit Polyclonal anti-Calreticulin antibody (ABIN6297924) specifically detects Calreticulin. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Calreticulin antibody (ABIN6297924)

Target: Calreticulin (CALR)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calreticulin antibody is un-conjugated

Application: Please inquire

Product Details anti-Calreticulin Antibody

Purpose: Rabbit Anti-CALR Antibody,

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Calreticulin

Target: Calreticulin (CALR)

Alternative Name: CALR

Background:

Target Description: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).

Gene Symbol: CALR

Gene ID: 811

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response