CES1 antibody
Quick Overview for CES1 antibody (ABIN629796)
Target
See all CES1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Purified
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Immunogen
- Carboxylesterase 1 antibody was raised using a synthetic peptide corresponding to a region with amino acids ANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNL
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Application Notes
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WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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Carboxylesterase 1 Blocking Peptide, (ABIN936783), is also available for use as a blocking control in assays to test for specificity of this Carboxylesterase 1 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CES1 antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- CES1 (Carboxylesterase 1 (CES1))
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Alternative Name
- Carboxylesterase 1
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Background
- CES1 is one of the enzymes responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia.
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Molecular Weight
- 62 kDa (MW of target protein)
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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