ERI1 antibody (C-Term)
Quick Overview for ERI1 antibody (C-Term) (ABIN629880)
Target
See all ERI1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- THEX1 antibody was raised against the C terminal of theX1
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Purification
- Purified
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Immunogen
- THEX1 antibody was raised using the C terminal of theX1 corresponding to a region with amino acids GSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIM
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Application Notes
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WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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THEX1 Blocking Peptide, (ABIN938983), is also available for use as a blocking control in assays to test for specificity of this THEX1 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of THEX1 antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- ERI1 (Exoribonuclease 1 (ERI1))
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Alternative Name
- THEX1
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Background
- THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi).
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Molecular Weight
- 38 kDa (MW of target protein)
Target
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