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ERI1 antibody (C-Term)

This anti-ERI1 antibody is a Rabbit Polyclonal antibody detecting ERI1 in WB. Suitable for Human, Mouse, Rat and Dog.
Catalog No. ABIN629880

Quick Overview for ERI1 antibody (C-Term) (ABIN629880)

Target

See all ERI1 Antibodies
ERI1 (Exoribonuclease 1 (ERI1))

Reactivity

  • 42
  • 35
  • 19
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Mouse, Rat, Dog

Host

  • 58
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Rabbit

Clonality

  • 58
  • 2
Polyclonal

Conjugate

  • 30
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ERI1 antibody is un-conjugated

Application

  • 34
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  • 13
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  • 12
  • 8
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  • 4
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  • 3
  • 1
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Western Blotting (WB)
  • Binding Specificity

    • 15
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    • 1
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    C-Term

    Specificity

    THEX1 antibody was raised against the C terminal of theX1

    Purification

    Purified

    Immunogen

    THEX1 antibody was raised using the C terminal of theX1 corresponding to a region with amino acids GSWDMSKFLNIQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIM
  • Application Notes

    WB: 2.5 µg/mL
    Optimal conditions should be determined by the investigator.

    Comment

    THEX1 Blocking Peptide, (ABIN938983), is also available for use as a blocking control in assays to test for specificity of this THEX1 antibody

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of THEX1 antibody in PBS

    Concentration

    Lot specific

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target

    ERI1 (Exoribonuclease 1 (ERI1))

    Alternative Name

    THEX1

    Background

    THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi).

    Molecular Weight

    38 kDa (MW of target protein)
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