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UPF3B antibody

UPF3B Reactivity: Human, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN629921
  • Target See all UPF3B Antibodies
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    Reactivity
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Dog
    Host
    • 14
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    This UPF3B antibody is un-conjugated
    Application
    • 9
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    Purified
    Immunogen
    UPF3 B antibody was raised using a synthetic peptide corresponding to a region with amino acids MKEEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEAL
    Top Product
    Discover our top product UPF3B Primary Antibody
  • Application Notes
    WB: 1.25 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    UPF3B Blocking Peptide, catalog no. 33R-6132, is also available for use as a blocking control in assays to test for specificity of this UPF3B antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of UPF0 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    Alternative Name
    UPF3B (UPF3B Products)
    Synonyms
    HUPF3B antibody, MRXS14 antibody, RENT3B antibody, UPF3X antibody, 5730594O13Rik antibody, AI317193 antibody, AW541158 antibody, RGD1560264 antibody, UPF3B, regulator of nonsense mediated mRNA decay antibody, UPF3 regulator of nonsense transcripts homolog B (yeast) antibody, UPF3B antibody, Upf3b antibody
    Background
    UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions.
    Molecular Weight
    52 kDa (MW of target protein)
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