HIST2H2AA3 antibody (Middle Region)

Catalog No. ABIN630177

Product Details anti-HIST2H2AA3 Antibody

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST2H2AA3 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: HIST2 H2 A3 antibody was raised against the middle region of HIST2 2 A3

Purification: Purified

Immunogen: HIST2 H2 A3 antibody was raised using the middle region of HIST2 2 A3 corresponding to a region with amino acids PRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK

Application Details

Application Notes: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HIST2H2AA3 Blocking Peptide, catalog no. 33R-7325, is also available for use as a blocking control in assays to test for specificity of this HIST2H2AA3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HIST0 0 A3 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for HIST2H2AA3

Target: HIST2H2AA3 (Histone Cluster 2, H2aa3 (HIST2H2AA3))

Alternative Name: HIST2H2AA3 (HIST2H2AA3 Products)

Synonyms: H2A antibody, H2A.2 antibody, H2A/O antibody, H2A/q antibody, H2AFO antibody, H2a-615 antibody, HIST2H2AA antibody, Hist2h2aa antibody, Hist2h2aa1 antibody, histone cluster 2 H2A family member a3 antibody, histone cluster 2 H2A family member A3 antibody, HIST2H2AA3 antibody, Hist2h2aa3 antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AA3 is a member of the histone H2A family.

Molecular Weight: 14 kDa (MW of target protein)

Pathways: Telomere Maintenance