Adenylate Kinase 1 antibody (N-Term)

Catalog No. ABIN631113

This anti-Adenylate Kinase 1 antibody is a Rabbit Polyclonal antibody detecting Adenylate Kinase 1 in WB. Suitable for Human.

Quick Overview for Adenylate Kinase 1 antibody (N-Term) (ABIN631113)

Target: Adenylate Kinase 1 (AK1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenylate Kinase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Adenylate Kinase 1 Antibody

Binding Specificity: N-Term

Specificity: AK1 antibody was raised against the N terminal of AK1

Purification: Affinity purified

Immunogen: AK1 antibody was raised using the N terminal of AK1 corresponding to a region with amino acids HLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVN

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

AK1 Blocking Peptide, (ABIN939176), is also available for use as a blocking control in assays to test for specificity of this AK1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of AK1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for Adenylate Kinase 1

Target: Adenylate Kinase 1 (AK1)

Alternative Name: AK1

Background: Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.

Molecular Weight: 22 kDa (MW of target protein)

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process