SPTLC2 antibody (N-Term)

Catalog No. ABIN631161

This anti-SPTLC2 antibody is a Rabbit Polyclonal antibody detecting SPTLC2 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for SPTLC2 antibody (N-Term) (ABIN631161)

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPTLC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPTLC2 Antibody

Binding Specificity: N-Term

Specificity: SPTLC2 antibody was raised against the N terminal of SPTLC2

Purification: Affinity purified

Immunogen: SPTLC2 antibody was raised using the N terminal of SPTLC2 corresponding to a region with amino acids VLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENF

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SPTLC2 Blocking Peptide, (ABIN5616385), is also available for use as a blocking control in assays to test for specificity of this SPTLC2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SPTLC2 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for SPTLC2

Target: SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))

Alternative Name: SPTLC2

Background: SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.

Molecular Weight: 63 kDa (MW of target protein)