EPS15 antibody (C-Term)

Catalog No. ABIN631791

This anti-EPS15 antibody is a Rabbit Polyclonal antibody detecting EPS15 in WB. Suitable for Human and Mouse.

Quick Overview for EPS15 antibody (C-Term) (ABIN631791)

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPS15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPS15 Antibody

Binding Specificity: C-Term

Specificity: EPS15 antibody was raised against the C terminal of EPS15

Purification: Affinity purified

Immunogen: EPS15 antibody was raised using the C terminal of EPS15 corresponding to a region with amino acids LDSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDPFTSATTTTNKEADPSNF

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

EPS15 Blocking Peptide, (ABIN940254), is also available for use as a blocking control in assays to test for specificity of this EPS15 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EPS15 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for EPS15

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Alternative Name: EPS15

Background: EPS15 is a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias.

Molecular Weight: 99 kDa (MW of target protein)

Pathways: EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation