RBMXL2 antibody (Middle Region)

Catalog No. ABIN633231

Product Details anti-RBMXL2 Antibody

Target: RBMXL2 (RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBMXL2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: RBMXL2 antibody was raised against the middle region of RBMXL2

Purification: Affinity purified

Immunogen: RBMXL2 antibody was raised using the middle region of RBMXL2 corresponding to a region with amino acids SSRDGYSSRDYREPRGFAPSPGEYTHRDYGHSSVRDDCPLRGYSDRDGYG

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RBMXL2 Blocking Peptide, catalog no. 33R-8844, is also available for use as a blocking control in assays to test for specificity of this RBMXL2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RBMXL2 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for RBMXL2

Target: RBMXL2 (RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2))

Alternative Name: RBMXL2 (RBMXL2 Products)

Synonyms: HNRNPG-T antibody, HNRNPGT antibody, HNRPGT antibody, 1700012H05Rik antibody, Hnrnpg-t antibody, RBMX antibody, hnRNP G-T antibody, RNA binding motif protein, X-linked like 2 antibody, RNA binding motif protein, X-linked-like 2 antibody, RBMXL2 antibody, Rbmxl2 antibody

Background: The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.

Molecular Weight: 43 kDa (MW of target protein)