SRGN antibody (Middle Region)
Quick Overview for SRGN antibody (Middle Region) (ABIN633597)
Target
See all SRGN AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Specificity
- Serglycin antibody was raised against the middle region of SRGN
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Purification
- Affinity purified
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Immunogen
- Serglycin antibody was raised using the middle region of SRGN corresponding to a region with amino acids RTDLFPKTRIQDLNRIFPLSEDYSGSGFGSGSGSGSGSGSGFLTEMEQDY
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Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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Serglycin Blocking Peptide, ABIN5616055, is also available for use as a blocking control in assays to test for specificity of this Serglycin antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SRGN antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- SRGN (serglycin (SRGN))
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Alternative Name
- Serglycin
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Background
- SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.
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Molecular Weight
- 15 kDa (MW of target protein)
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Pathways
- Maintenance of Protein Location
Target
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