SMC4 antibody (Middle Region)

Catalog No. ABIN634091

The Rabbit Polyclonal anti-SMC4 antibody has been validated for WB. It is suitable to detect SMC4 in samples from Human and Rat.

Quick Overview for SMC4 antibody (Middle Region) (ABIN634091)

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMC4 Antibody

Binding Specificity: Middle Region

Specificity: SMC4 antibody was raised against the middle region of SMC4

Purification: Affinity purified

Immunogen: SMC4 antibody was raised using the middle region of SMC4 corresponding to a region with amino acids EARCHEMKPNLGAIAEYKKKEELYLQRVAELDKITYERDSFRQAYEDLRK

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SMC4 Blocking Peptide, (ABIN937666), is also available for use as a blocking control in assays to test for specificity of this SMC4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SMC4 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for SMC4

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Alternative Name: SMC4

Background: SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Molecular Weight: 147 kDa (MW of target protein)