CD40 Ligand antibody
Quick Overview for CD40 Ligand antibody (ABIN634665)
Target
See all CD40 Ligand (CD40LG) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Affinity purified
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Immunogen
- CD40 L antibody was raised using a synthetic peptide corresponding to a region with amino acids ENSFEMQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLEN
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Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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CD40L Blocking Peptide, (ABIN938001), is also available for use as a blocking control in assays to test for specificity of this CD40L antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CD40 G antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- CD40 Ligand (CD40LG)
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Alternative Name
- CD40L
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Background
- CD40LG is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
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Molecular Weight
- 29 kDa (MW of target protein)
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Pathways
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
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