Kallikrein 11 antibody (AA 68-82)
Quick Overview for Kallikrein 11 antibody (AA 68-82) (ABIN636296)
Target
See all Kallikrein 11 (KLK11) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 68-82
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Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
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Cross-Reactivity (Details)
- This antibodys immunogen shares 86 % sequence identity with the Mouse, and rat homologs.
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Purification
- Affinity chromatography purified
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Immunogen
- KLK11 antibody was raised in rabbit using AA 68-82 [YIVHLGQHNLQKEEG] of the 35 kDa human hippostasin/KLK11 protein as the immunogen.
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Isotype
- IgG
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Application Notes
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WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- Affinity purified IgG supplied in PBS with 0.02 % NaN3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Kallikrein 11 (KLK11)
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Alternative Name
- KLK11
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Background
- Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of hK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer.
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Pathways
- Complement System
Target
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