TUBB3 antibody (AA 433-450)

Catalog No. ABIN636326

The Rabbit Polyclonal anti-TUBB3 antibody is suitable to detect TUBB3 in samples from Human. It has been validated for WB.

Quick Overview for TUBB3 antibody (AA 433-450) (ABIN636326)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBB3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TUBB3 Antibody

Binding Specificity: AA 433-450

Cross-Reactivity (Details): This antibodys immunogen shares 94 % sequence identity with the Mouse homolog, and 100 % with the rat homolog.

Purification: Affinity purified

Immunogen: TUJ1 antibody was raised in rabbit using AA 433-450 EGEMYEDDEEESEAQGPK of the 50 kDa human beta-tubulin-III protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: TUJ1

Background: The beta-tubulin III protein (also know as Tuj 1) belongs to the tubulin superfamily and is abundant in the brain, where it is expressed almost exclusively in neurons after differentiation. There are significant post-translational modifications made to beta-tubulin III with numerous isoforms present during early post-natal neural development. Altered patterns of expression are noted in brain tumors such as medulloblastomas.

Pathways: Microtubule Dynamics, M Phase