WB: >1:1,000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
Supplied as serum.
Precaution of Use
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target
HNE
(4-Hydroxynonenal (HNE))
Target Type
Chemical
Background
4-Hydroxynonenal (HNE) is a highly reactive, cytotoxic aldehyde. HNE can efficiently react with sulfhydryl groups or histidine and lysine groups of proteins to form stable HNE-protein adducts, in addition to phospholipids and nucleic acids. It is through this HNE-modification of biomolecules that HNE is thought to exert its cytotoxic effects.