T-Box 1 antibody

Catalog No. ABIN636370

This Rabbit Polyclonal antibody specifically detects T-Box 1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for T-Box 1 antibody (ABIN636370)

Target: T-Box 1 (TBX1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-T-Box 1 Antibody

Cross-Reactivity (Details): This antibodys immunogen sequence shares 80 % sequence identity with the Mouse homolog, and 86 % sequence identity with the rat homolog.

Purification: Affinity chromatography purified

Immunogen: Brachyury antibody was raised in rabbit using the internal sequence of the human Brachyury protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: IHC: 1:100-1:250, WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified and supplied in PBS, with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for T-Box 1

Target: T-Box 1 (TBX1)

Alternative Name: Brachyury

Background: The Brachyury protein is required for the proper formation and differentiation of posterior mesoderm and for axial development in all vertebrates. The Brachyury gene encodes a transcription factor that binds to a specific DNA element via its N-terminal region.

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation