TNFSF14 antibody

Catalog No. ABIN636620

The Rabbit Polyclonal anti-TNFSF14 antibody is suitable to detect TNFSF14 in samples from Human. It has been validated for WB, ELISA and InhibAb.

Quick Overview for TNFSF14 antibody (ABIN636620)

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFSF14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Product Details anti-TNFSF14 Antibody

Purification: Purified

Immunogen: LIGHT antibody was raised in rabbit using highly pure recombinant human LIGHT as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for TNFSF14

Target: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Background: LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.

Molecular Weight: 20.1 kDa (predicted detection band MW)

Pathways: Cancer Immune Checkpoints