Follistatin antibody
Quick Overview for Follistatin antibody (ABIN636639)
Target
See all Follistatin (FST) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Purified
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Immunogen
- Follistatin antibody was raised in rabbit using highly pure recombinant human Follistatin as the immunogen.
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Application Notes
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ELISA: 0.5-2 µg/mL, Inhibition: 8-12 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Follistatin (FST)
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Alternative Name
- Follistatin
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Background
- Follistatin is a secreted protein that binds to ligands of the TGF beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues.
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Molecular Weight
- 31.5 kDa (predicted detection band MW)
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Pathways
- Negative Regulation of Hormone Secretion
Target
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