ApoE3 antibody
Quick Overview for ApoE3 antibody (ABIN636657)
Target
See all ApoE3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Purified
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Immunogen
- ApoE3 antibody was raised in rabbit using highly pure recombinant human ApoE3 as the immunogen.
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Application Notes
- Optimal conditions should be determined byt he investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- ApoE3 (Apolipoprotein E3 (ApoE3))
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Alternative Name
- ApoE3
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Background
- ApoE3 belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE exists in three major isoforms, E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population.
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Molecular Weight
- 34 kDa (predicted detection band MW)
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Pathways
- Regulation of Cell Size, Lipid Metabolism
Target
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