ARTN antibody

Catalog No. ABIN636663

Product Details anti-ARTN Antibody

Target: ARTN (Artemin (ARTN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARTN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Purified

Immunogen: Artemin antibody was raised in rabbit using highly pure recombinant human artemin as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for ARTN

Target: ARTN (Artemin (ARTN))

Alternative Name: Artemin (ARTN Products)

Synonyms: ARTN antibody, ENOVIN antibody, EVN antibody, NBN antibody, neublastin antibody, artemin antibody, ARTN antibody, Artn antibody

Background: Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRalpha (alpha1-alpha4) receptors. Artemin prefers the receptor GFRalpha3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia such as sympathetic, neural crest and placodally derived sensory neurons, and dompaminergic midbrain neurons.

Molecular Weight: 24.2 kDa (predicted detection band MW)