GPR37L1 antibody

Catalog No. ABIN636877

Product Details anti-GPR37L1 Antibody

Target: GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR37L1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity chromatography purified

Immunogen: GPR37 L1 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Application Details

Application Notes: IHC-P: 10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

References for anti-GPR37L1 antibody (ABIN636877)

Ehrenreich, Nau, Dembowski, Hasselblatt, Barth, Hahn, Schilling, Sirén A-L, Brück: "Endothelin b receptor deficiency is associated with an increased rate of neuronal apoptosis in the dentate gyrus." in: Neuroscience, Vol. 95, Issue 4, pp. 993-1001, (2000) (PubMed).

Target Details for GPR37L1

Target: GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))

Alternative Name: GPR37L1 (GPR37L1 Products)

Synonyms: GPR37L1 antibody, ET(B)R-LP-2 antibody, ETBR-LP-2 antibody, AW047233 antibody, CAG-18 antibody, D0Kist8 antibody, G protein-coupled receptor 37 like 1 antibody, G protein-coupled receptor 37-like 1 antibody, GPR37L1 antibody, Gpr37l1 antibody

Background: Endothelin receptor type B is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Two splice variants have been identified both of which bind ET1 but exhibit different responses upon binding which suggests that they may be functionally distinct.