USP20 antibody

Catalog No. ABIN637001

Product Details anti-USP20 Antibody

Target: USP20 (Ubiquitin Specific Peptidase 20 (USP20))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP20 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity chromatography purified

Immunogen: USP20 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Application Details

Application Notes: IHC-P: 10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Target Details for USP20

Target: USP20 (Ubiquitin Specific Peptidase 20 (USP20))

Alternative Name: USP20 (USP20 Products)

Synonyms: USP20 antibody, vdu2 antibody, lsfr3a antibody, LSFR3A antibody, VDU2 antibody, hVDU2 antibody, 1700055M05Rik antibody, AI467231 antibody, Vdu2 antibody, im:7151955 antibody, zgc:63661 antibody, universal stress protein antibody, ubiquitin specific peptidase 20 antibody, ubiquitin specific peptidase 20 L homeolog antibody, RR_RS15875 antibody, USP20 antibody, usp20 antibody, Usp20 antibody, usp20.L antibody

Background: USP20 is a deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. It acts as a regulator ofG-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2) and plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutivelybinding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling