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USP20 antibody
USP20
Reactivity: Human
IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-USP20 Antibody
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Target
See all USP20 Antibodies
USP20
(Ubiquitin Specific Peptidase 20 (USP20))
Reactivity
All reactivities for USP20 antibodies
Human
Host
All hosts for USP20 antibodies
Rabbit
Clonality
All clonalities for USP20 antibodies
Polyclonal
Conjugate
All conjugates for USP20 antibodies
This USP20 antibody is un-conjugated
Application
All applications for USP20 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Affinity chromatography purified
Immunogen
USP20 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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Application Details
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Application Notes
IHC-P: 10 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
Target Details for USP20
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Target
USP20
(Ubiquitin Specific Peptidase 20 (USP20))
Alternative Name
USP20 (USP20 Products )
Synonyms
USP20 antibody, vdu2 antibody, lsfr3a antibody, LSFR3A antibody, VDU2 antibody, hVDU2 antibody, 1700055M05Rik antibody, AI467231 antibody, Vdu2 antibody, im:7151955 antibody, zgc:63661 antibody, universal stress protein antibody, ubiquitin specific peptidase 20 antibody, ubiquitin specific peptidase 20 L homeolog antibody, RR_RS15875 antibody, USP20 antibody, usp20 antibody, Usp20 antibody, usp20.L antibody
Background
USP20 is a deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. It acts as a regulator ofG-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2) and plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutivelybinding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2.
Pathways
Regulation of G-Protein Coupled Receptor Protein Signaling
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