CD40 antibody (Extracellular Domain)

Catalog No. ABIN6383879

This Mouse Monoclonal antibody specifically detects CD40 in IHC. It exhibits reactivity toward Human.

Quick Overview for CD40 antibody (Extracellular Domain) (ABIN6383879)

Target: CD40

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: C40-2383

Product Details anti-CD40 Antibody

Binding Specificity: AA 29-107, Extracellular Domain

Purpose: CD40

Purification: By Protein A from bioreactor concentrate

Immunogen: Recombinant fragment around aa 29-107 of human CD40 protein (exact sequence is proprietary)

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

L-428, tonsil, spleen, thymus

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg IgG/mL in PBS, 0.05 % azide

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage Comment: For long term storage, keep small aliquots at -20°C or -80°C and keep one aliquot at 4°C for daily experimentations. Azide will preserve antibody at 4°C for 6-12 months, when kept away from direct sun light.

Target Details for CD40

Target: CD40

Alternative Name: CD40

Background: CD40 Molecule, Bp50, CDW40, TNFRSF5, p50, B-cell surface antigen CD40, CD40L receptor, CD_antigen: CD40, Tumor necrosis factor receptor superfamily member 5

Gene ID: 958

UniProt: P25942

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints